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Guest Lecturer — BM3110: Electronic Instrumentation

Dept. of Biomedical Engineering · University of Moratuwa, Sri Lanka · Semester 5 Undergraduates · Fall 2026

I delivered a series of lectures on electronic instrumentation to third-year Biomedical Engineering undergraduates at the University of Moratuwa, centred on a question every biomedical measurement system faces: how do you recover a microvolt-level signal from a noisy, interference-filled world? The series builds from the fundamentals of noise, through transistor and op-amp noise models and the physics of interference, to PCB layout and a complete ECG front-end design. Each lecture below has a written summary — key equations, worked examples and diagrams — and the full slides as a PDF.

7 lectures · 264 slides in total


Noise & interference in instrumentation

1Part 1: Introduction

where noise comes frommodelling noisy devices (1-port & 2-port)RMS, mean & power spectral densitywhen noise powers addnoise through a frequency-dependent systemnoise figure

The toolkit for everything that follows: representing noise sources in a circuit, quantifying them, knowing when they can be added, propagating them through a filter, and comparing a system against a reference with the noise figure.

2Part 2: Classification of Noise

thermal (Johnson–Nyquist) noisecombining noise sourcesRC filter noise bandwidthshot noise1/f (flicker) noiseburst (popcorn) noise

A working, quantitative picture of where random noise in an instrumentation circuit comes from, classified by the physical mechanism that produces it, and how to combine the sources correctly.

3Part 3: Modelling Diode and BJT Noise

diode small-signal modeldiode shot, flicker and thermal noiseBJT hybrid-π modelthe six BJT noise sourcesinput-referred noiseeffect of source impedance

Turns the noise toolkit into transistor-level models: small-signal models for the diode and BJT, their noise sources, and how to refer them to the input. The key lesson is that a two-port needs both a voltage and a current noise source, and that these can be correlated.

4Part 4: The Op-Amp Noise Model

op-amp as a multi-portthe standard noise modeldatasheet noise valuestotal output noise of an inverting amplifierthe effect of source impedancechoosing a low-noise amplifier

Replaces transistor-level detail with the standard three-source op-amp noise model, then works a full inverting-amplifier example and shows how source resistance decides which noise term dominates — and therefore which amplifier to choose.

5Part 5: Interference, Coupling and Mitigation

source–coupling–receiver modelcapacitive, inductive and conductive couplingshieldingtwisted pairsground loops and groundingisolationCMRR and differential signallingpower-line interferenceADC noise

The longest lecture of the series: everything about interference that enters from outside the circuit. Each coupling mechanism is modelled quantitatively, paired with its mitigation, and the lecture closes with power-line filters, data-acquisition noise and ADC quantisation noise.

6Part 6: Best Practices for PCB Design

layout processcrosstalktracesshared ground impedanceguard ringsdecoupling capacitorssplitting analog and digitalECG PCB assignment and power-tree design rationale

Turns the interference theory of Part 5 into layout rules, then applies it to a graded group assignment: a battery-powered wearable ECG board, with a worked rationale for its power tree, ADC choice and reference voltage.

Signal conditioning

7Signal Conditioning — Designing an ECG Front-End

displacement currentsmains coupling into the human bodycommon-mode and differential interference in an ECGelectrode offset voltagedifference amplifier vs instrumentation amplifierdriven-right-leg circuit

A start-to-finish case study: how 50 Hz mains reaches an ECG through capacitive coupling, why each effect appears as common-mode or differential interference, and how the instrumentation amplifier and driven-right-leg circuit tackle them.

Slides are PDF exports of the original PowerPoint decks.

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